Hi there!
I am already planning my next knitting project: socks for DH for 2nd anniversary. I have never made socks before but really want to try them. I have heard that making them on two circulars helps with keeping them consistent.
Unless his foot is especially wide, you probably will not need to adjust the pattern. Just knit the foot portion longer than you would for a woman. Start the toe decreases when the sock (from the turned heel to the needles) is 2 inches shorter than his foot from heel to toe.
If his foot IS wide, knit them on needles one size larger.