Placeholders in lace

I am still confused about the placeholders. I have a pattern that starts the first row with 3 placeholders. Do I just pull them off and start on the fourth stitch? If I go to the4th stitch and just start to knit, it seems very awkward.

Do you mean ‘no stitch’ placeholders in a chart? You start on the 4th st in the chart, but do it on the first stitch.