I've considered the SnB that meets at The Knit Nook on Bardstown Road on Thursday evenings (and maybe Sunday afternoons).
I briefly attended an intentional community group, Knit Together, which is part of the Covenant Community Church in the Clifton neighborhood http://www.cccoflouisville.org/welcome.html. I work with one of the women in that group, and I enjoyed it. I had a conflicting commitment on the same night that I hated to give up.
There are also quite a few people interested in knitting in the Louisville area on meetup.com. I expect all it would take to get something going there would be for someone to schedule a time/place and let people know about it.
Good luck! I'd also like to have someone to help me figure out the stuff I have so much trouble with.
Joe in New Albany, IN (across the river from Louisville)