I don't have a favorite pattern for blankets; rather, I just make whatever pattern seems to "call out" to me. As for colors, you can certainly choose pastels--mint green, peach, or yellow work well for not knowing the genders (as do off-white and white)--but for me personally, I prefer to make things in bolder colors or neutrals. Tan, forest green, burgundy, navy, brown, grey--they all work well. Bright colors also work great because kids and babies look good in brights, too, and they're fun for kids. I don't know if there's a hard and fast "rule" for colors. If you're still stuck on colors, you can also consider choosing a color that the mom and/or dad like too, because they will be toting the blanket around with them. Of you can choose a color based off of whatever color that the nursery will be if you happen to know that information.